Silicon nanotube arrays deliver functional mRNA into human pluripotent stem cells for the first time, achieving up to 64% transfection without compromising stem cell identity.
When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether the mRNA ...
SEATTLE and TELFORD, Pa., Feb. 05, 2026 (GLOBE NEWSWIRE) -- Pluristyx, Inc., a leading provider of induced pluripotent stem cell (iPSC)-based technologies, and Solesis, a leader in applied biomaterial ...
Transfection is a crucial non-viral technique for introducing DNA or RNA into cells, yet achieving high efficiency and consistency can be challenging, particularly with difficult cell types.
Modifying gene-delivery approaches for lymphocytes is critical for both fundamental research and clinical immunotherapy. T cells, B cells, and natural killer (NK) cells are difficult to transfect, and ...
In a recent article in Molecular Therapy, Sanofi presented preclinical data for an in vivo CAR-T platform that reengineers T ...
A major bottleneck in curing HIV (human immunodeficiency virus) is that the virus can hide in an inactive form within resting white blood cells, which play a crucial role in coordinating the immune ...
Researchers at Harvard Medical School and Brigham and Women's Hospital designed an ingestible capsule that delivers liquid mRNA to the intestines, producing gene expression and reducing inflammation ...
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