Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...
The exposure to low doses of stress induces an adaptive survival response that involves the upregulation of cellular defense systems such as heat shock proteins (Hsps), anti-apoptosis proteins, and ...
DDX10 deletion promotes CRC cell apoptosis through ATG10-driven autophagy Aug. 21, 2024 ...
Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control ...
A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy. This ...
In a recent study published in the journal Neuron, researchers at the University of Cambridge and Newcastle University, UK, examined the relationship between autophagy, aging, and neurodegeneration.
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